Comment on: Malignant hypertension and nephrotic range proteinuria without hematuria: IgA nephropathy

[IgA nephropathy with malignant hypertension].

症 例 患者:29歳,女 性.主 訴:頭 痛,高 血圧.既 往歴,家 族歴:特 記すべ きことな し.現 病歴: 1995年 よ り尿 蛋白,1998年 よ り高血圧 を指摘 さ れる も放置.こ の ころか ら頭痛発作 を繰 り返 し ていた.2000年 の検診で高血圧,尿 蛋 白,尿 潜 血,貧 血,心 電 図異常 を指摘 され,同 年7月13 日当院を初診.初 診時身体所見:意 識清明,身 長160cm,体 重52kg,体 温36.8°C,血 圧240/140 孤mHg,上 下肢差 ・左右差な し,脈 拍80/分 整, 胸 部にラ音 ・心雑音 を聴取せ ず.腹 部平坦軟, 血管雑音 を聴取 せず.下 腿 に浮腫 な し.胸 水 ・ 腹水 を認めず.神 経学 的異常所 見な し.眼 底に 高血圧性 網膜症(Keith-Wagener III度)を 認め, 悪性高血圧B群 と診断 ...

Idiopathic Hypereosinophilic Syndrome Presenting as IgA Nephropathy with Nephrotic Range Proteinuria

Idiopathic hypereosinophilic syndrome (IHES) is a disorder characterized by increased eosinophil count (eosinophilia) along with organ dysfunction secondary to organ infiltration of eosinophils and release of inflammatory markers [1-4], with no obvious cause for eosinophilia. The onset of symptoms is insidious in most of the cases and eosinophilia is detected incidentally. However, in others, t...

Comment on: Clinical, Histopathological and Immunofluorescent Findings of IgA Nephropathy

Clinicopathological features and outcomes of IgA nephropathy with hematuria and/or minimal proteinuria.

BACKGROUND/AIMS Information regarding the clinical and histological prognostic factors of IgA nephropathy (IgAN) is mostly derived from patients in whom diagnostic renal biopsies were performed because their proteinuria levels were higher than 1-2 g/d. The clinicopathological features and outcomes of IgAN patients presenting with normal blood pressure, normal renal function, hematuria and minim...

Microfilariae-associated nephrotic range proteinuria.

A 50-year-old man presented with pedal edema and episodes of hematuria that had started 1 month before. Systemic examination revealed mild pedal edema and petechial rashes on both lower limbs, without lymphadenopathy. The urine color was noted to be milky white (Figure 1). Urine analysis showed 3þ albumin and numerous red blood cells. Urine spot protein creatinine ratio (PCR) was 14.8. Serum al...